FISH

Else Kröner-Fresenius-sSMC-cellbank

Else Kröner-Fresenius-cellbank
for small supernumerary marker chromosomes

 

Between 2010 and 2013 the Else Kröner-Fresenius foundation sponsors the establishment of a cellbank for sSMC (applicants: Dr. Thomas Liehr, Jena and Dr. Marianne Volleth, Magdeburg, Germany).

All up to now established and in Jena collected cell lines are included on this page (see below).

For research purposes these cell lines are available on reqeust for free ().
We only ask for the covering the costs the thawing, cell culture and mailing of the lines.
At least citation of this cell bank and acknowledgment for providing the cell lines is expected in any published paper using any of these lines. 

 

The nomenclature for cell lines is complex and explained here

 


 

 

 

 

 

 

               
  EKF-cellline
case no. 
GTG-banding result
grade of mosaicism
 
final result of the sSMC clinical symptoms/
reference
cellline of parents Identifier
(internal use)
 
  EKF-
#1-p11.1/
1-m
47,XY,+mar[17]/
46,XY[3]
min(1)(:p11.1q11:) see 01-CW-5 EKF-#1-p11.1/1-m-mother 12L0128
13L0176
 
  EKF-
#1-p11.1/
1-r
in cell line: 47,XY,+r[3]/
46,XY[47]
interphase: 16 of 200 cells
r(1)(::p11.1q22::)
array-CGH: 105.98-188.41MB
r(1)(::p21.1q31.1::)
see 01-W-p11.1/3-1 n.a. 05P0749  
  EKF-
#1-p11.1/
1-m
in cell line: 47,XX,+mar[59]/
46,XX[41]
min(1)(:p11.1q12:) see 01-O-p11.1/3-6 n.a. 12L0084  
  EKF-
#1-p11.1/
2-m
47,XX,+mar[100%] min(1)(:p11.1q12:) see
01-O-p11.1/3-1
n.a. 120L231  
  EKF-
#2-N/
1-r
47,XX,del(2)(q22q32.2),
+r(2)(q22q32.2)[81]/
46,XX,del(2)(q22q32.2)[9]
n.a. see McCl-02-N-q35/1-1 EKF-#2-N/1-r-mother;
EKF-#2-N/1-r-father
05PO417
05PO418
05PO419
 
  EKF-
#2-p11.1/
1-m
in cell line: 47,XX,+mar[2]/
46,XX[98]
min(2)(:p11.1q11.2:) 
FISH-data: RP11-708D7: 95.0 MB
aCGH: 91.27-99.97
see 02-O-p11.1/5-1 EKF-#2-p11.1/1-m-father 12L0052
13L0077
 
  EKF-
#2-p11.1/
2-m
in cell line: 47,XX,+mar[20]/
46,XX[80]
min or r(2)(:p11.1q11.2:) 
FISH-data: RP11-708D7: 95.0 MB
see 02-O-p11.1/5-2 n.a. 12L0107  
  EKF-
#2-p11.2/
1-m
in cell line: 47,XY,+mar[1]/
46,XY[60]
interphase: 3 of 200 cells
 
min(2)(:p11.2q11.1:) 
FISH-data: RP11-303I4 (80.7MB); RP11-316G9 (89.7MB); RP11-271A22 = AC128677.4 (91.5MB)  on sSMC
see 02-W-p11.2/1-2 n.a. 2010B113  
  EKF-
#2-p11.2/
2-m/r
in cell line:
47,XY,+mar[6]/
46,XY[44]
interphase: 22 of 189 cells
 
r(2)(::p11.1q12.1::) 
91.01-101.58 MB
array: r(2)(::p11.2
q12.1::) 
see 02-O-p11.2/1-1 n.a. 06P0793  
  EKF-
#3-p12.1/
1-m/r
in cell line: 47,XX,+mar[39]/
46,XX[57]
interphase: 127 of 500 cells
r(3)(::p12.1q11.1::)[14]/ min(3)(:p12.1q11.1:)[5]/ min(3)(:p12.1q11.1:
:q11.1
p12.1:)[2]
FISH-d
ata: RP11-91A15 (89.6 MB) on sSMC
see 03-O-p12.1/2-2 n.a. 07PO736  
  EKF-
#4-p11/
1-m
47,XY,+mar[47]/
46,XY[13]
min(4)(:p11q12:)[9]/
min(4)(:q12
p11::p11q12:)[1]
see
04-W-p11/2-1
n.a. 12L0247  
  EKF-
#4-p11/
2-m
47,XY,+mar[62%]/
46,XY[38%]
min(4)(:p11q12:) see
04-O-p11.1/1-1
n.a. 13L0227  
  EKF-
#5-p13.2/
1-m

in cell line:
47,XY,+mar[1]/
46,XY[99]

min(5)(::p13.2q11.1::)
FISH-data:  break in p-arm between: 37.00-37.18 MB
see 05-W-p13.2/2-1 n.a. 12L0054  
  EKF-
#5-p13.2/
1-r
47,XY,+mar[7]/
46,XY[3]
r(5)(::p13.2q11.1::)[9]/
r(5;5)(::p13.2
q11.1:
:p13.2
q11.1::)[1]
see 05-W-p13.2/1-1 n.a. 12L0135  
  EKF-
#5-p12/
1-m
in cell line: 47,XX,+mar[54]/
46,XX[46]
min(5)(:p12q11.1:)
FISH-data:
RP11-19F12 (41.24MB) on sSMC
see 05-O-p12/1-1 n.a. 12L0077  
  EKF-
#6-p11.1/
1-m
48,XY,+marx2[59]/
47,XY,+mar[25]
46,XY[40]
min(6)(:p11.1q12:) see 06-W-p11.1/1-1 n.a. 05P0223  
  EKF-
#6-p11.1/
2-i
in cell line: 47,XY,+mar[1]/
46,XY[129]
interphase: 21 of 180 cells
dic(6;6)(:p11q11::p11q11:) see 06-O-p11.1/2-1 n.a. 11L013  
  EKF-
#7-p12/
1-m
in cell line: 47,XY,+mar[0]/
46,XY[50]

min(7)(:p12p11.1:)
maternal (iso-)disomy  UPD 7
aCGH: 44,864,487 Mb-57,562,142 MB

see
07-U-13
n.a. 12L0211  
  EKF-
#7-p11.2/
1-m

in cell line:
47,XX,+r[53]/
46,XX[47]

min(7)(:p11.2q11.1:)
FISH-data: RP11-10F11 (56.45 MB) on sSMC
aCGH: 45.07-64.85
maternal (iso-)disomy  UPD 7
see 07-U-14 EKF-#7-p11.2/1-m-father 12L0080
13L0113
 
  EKF-
#7-p11.2/
2-m
in cell line (mother):
4
7,XX,+mar[25]/
46,XX[20]
min(7)(:p11.2q11.1:)
FISH-da
ta: RP11-10F11 (56.45 MB)
see 07-O-p11.2/2-1 EKF-#7-p11.2/2-m-mother 13L0178
12L0130 and
13L0177
 
  EKF-
#7-p11.2/
1-m/r
in cell line: 47,XX,+mar[25]/
46,XX[75]
min(7)(:p11.2
q11.21:)[5]/
r(7)(::p11.2
q11.21::)[2]/
r(7;7)(::p11.2
q11.21:
:p11.2
q11.21::)[1]
55.42-63.45 MB
see 07-W-p11.2/1-2 EKF-#7-
p11.2/1-m-
mother;
EKF-#7-
p11.2/1-m-
father
05P0529
05P0530
05P0531  
 
  EKF-
#7-p11.1/
1-r
in cell line: 47,XX,+mar[42]/
46,XX[58]
r(7)(:p11.1q11.21:)[15]/
r(7;7)(:p11.1
q11.21:
:p11.1
q11.21:)[4]/
r(7;7;7;7)
(:p11.1
q11.21:
:p11.1
q11.21:
:p11.1
q11.21:
:p11.1
q11.21:)[1]
FISH-data: RP11-3N2  (63.22 MB) on sSMC
aCGH: 7p11.2-7q11.23 (56,115,171-74,208,699 MB), 2 copies
see 07-W-p11.1/2-1  n.a. 12L0102  
  EKF-
#7-p11.1/
1-m
in cell line: 47,XX,+mar[15]/
46,XX[81]
interphase: 49 of 500 cells
min(7)(:p11.1q11.1:) see 07-W-p11.1/1-1 n.a. 06PO708  
  EKF-
#8-p11.21~
11.22/
1-r
in cell line: 47,XY,+mar[79]/
46,XY[21]
r(8)(::p11.21~11.22q11.1::)
FISH-data:
42.5-49.5 MB
see
08-W-p11.21~
11.22/1-1
EKF-#8-
p11.21~
11.22/1-r-
mother;
EKF-#8-
p11.21~
11.22/1-
r-father
2008B113
2008B112
2008B111
 
  EKF-
#8-p11.21/
1-m/r
47,XX,+mar[8]/
46,XX[7]
min(8)(:p11.21q11.21:)[8]/
min(8)(:p11.21
q11.1:)[3]/
min(8)(:p11.21
q11.1:
:q11.1
p11.21:)[1]/
r(8)(:p11.21
q11.1:
:q11.1
p11.21::q11.21::)[2]
see
08-U-6
n.a. 12L0184  
  EKF-
#8-p11/
1-m
in cell line:
47,XX,+mar[7]/
46,XX[43]
min(8)(:p11q11:)  see
08-O-p11/1-2
n.a. 12L0230  
  EKF-
#8-p11.1/
1-m
47,XY,+mar[70%]/
46,XY[30%]
min(8)(:p11.1q11.23:)
FISH-data: RP13-116A4 at 48.3MB on sSMC
Array: 43.19-54.86 MB
see
08-W-p11/2-1
EKF-#8-p11.1/1-m-mother 07PO597
07PO596
 
  EKF-
#8-p10/
1-r
in cell line:
47,XY,+r[8]/
46,XY[43]
r(8)(::p10q23.3::) see
08-W-p10/1-1
n.a. 12L0256  
  EKF-
#9-p12/
1-m/r
47,XY,+mar[90%]/
46,XY[10%]
r(9)(::p12q12::)[8]/
min(9)(:p12
q12:)[5]/
r(9;9)(::p12
q12:
:p12
q12::)[2]
see 09-O-p12/3-2 n.a. 2009B022  
  EKF-
#9-p12/
2-m/r
51,XX,+mar1,+mar2x4[1]/
49,XX,+mar1x2,+mar3[1]/
48,XX,+mar1,+mar2[9]/
48,XX,+mar1,+mar3[5]/
47,XX,+mar2[2]/
47,XX,+mar3[1]/
46,XX[1]
mar1 =
min(9)(:p12
q10:)
mar2 =
min(9)(:p11.1
q12:)
mar3 = r(9)(::p11.1
q12::)
see 09-O-p12/6-1 EKF-#9-p12/2-m/r-mother
EKF-#9-p12/2-m/r-father
12L0146
13L0158'
13L0159
 
  EKF-
#9-p12/
3-m/r
in cell line:
47,XY,+r[25]/
46,XY[25]
r(9)(::p12q12::)[6]/
min(9)(:p12
q12:)[4]
see 09-O-p12/4-2 n.a. 12L0225  
  EKF-
#9-p12/
1-r
in cell line:
47,XY,+r[5]/
46,XY[95]
r(9)(::p12q12::) see 09-O-p12/4-1 n.a. 12L0117  
  EKF-
#9-p11.1/
1-m
in cell line:
47,XX,+mar[1]/
46,XX[49]
min(9)(:p11.1q12:) see
09-W-p11.1/1-1 
n.a. 12L0174  
  EKF-
#9-p10/
1-m
in cell line:
47,+mar[0]/
46[50]
min(9)(:p10q13:) see
09-O-p10/1-1
n.a. 12L0196  
  EKF-
#12-p11.1/
1-m
in cell line:
47,XY,+r[7]/
46,XY[43]
min(12)(:p11.1q12:) see
12-W-p11.1/1-1 
EKF-#12-p11.22/1-m-mother 12L0200
13L0087
 
  EKF-
#12-p11.22/
1-m
in cell line:
47,XX,+mar[26]/
46,XX[24]
min(12)(:p11.22q11:) see 12-O-p11.22/1-1 EKF-#12-p11.22/
1-m-mother
EKF-#12-p11.22/
1-m-father
12L0161
13L0087
13L0237
 
  EKF-
#13/21-q11/
1-i

in cell line:
48,XY,+21,+mar pat[100%]

inv dup(13or21)(q10) see +21-U-38 EKF-#13/21-q11/
1-i-father
2010B211
2010B212
 
  EKF-
#13/21-q11/
2-i
in cell line:

47,XX,+mar pat[32]/
46,XX[11]

in cell line of father: 47,XY,+mar[42]/
46,XY[8]

in cell line of brother: 47,XY,+mar[10]/
46,XY[0]

inv dup(13or21)(q10) see
13/21-O-q10/1-16

EKF-#13/21-q11/
2-i-father;
EKF-#13/21-q11/
2-i-brother

12L0113
12L0114
13L0180

 
  EKF-
#13/21-q11/
3-i

in cell line:
47,XX,+mar mat[26]/
46,XX[4]

inv dup(13or21)(q10) see
13/21-O-q10/1-14
n.a.

12L0162

 
  EKF-
#13/21-q11/
4-i
in cell line:
47,XX,+mar[0]/
46,XX[50]
inv dup(13)(q11) or inv dup (21)(q11.1)

13/21-O-q11/2-14

n.a.

12L0126

 
  EKF-
#13/21-q11/
5-i
in cell line:

47,XX,+mar mat[39]/
46,XX[11]

in cell line of mother: 47,XX,+mar[20]/
46,XX[25]

inv dup(13or21)(q10) 13/21-O-q10/1-17 EKF-
#13/21-q11/
5-i-mother

12L0170
12L0171

 
  EKF-
#14-q11/
1-m

in cell line:
47,XY,+mar[25]/
46,XY[26]

min(14)(pterq11.1:)
maternal UPD 14
see 14-U-15 n.a. 12L0235  
  EKF-
#14-q11/
1-i
in cell line:
47,XX,+mar[14]/
46,XX[26]
inv dup(14)(q11) 14-O-q11/1-2 EKF-
#14-q11/
1-i-mother
EKF-
#14-q11/
1-i-father
12L0147
13L0219
13L0220
 
  EKF-
#14-q11.1/
1-i
in cell line:
47,XX,+mar[23]/
46,XX[19]
inv dup(14)(q11.1) see 14-O-q11.1/1-10 n.a. 06P0430  
  EKF-
#14-q11.1/
2-i
47,XX,+mar[100%] inv dup(14)(q11.1) see 14-O-q11.1/1-14 n.a. 07PO567  
  EKF-
#14-q11.1/
3-i
in cell line:
47,XY,+mar[44]/
46,XY[6]
inv dup(14)(q11.1) see 14-O-q11.1/1-29 n.a. 11L004  
  EKF-
#14-q11.1/
4-i
in cell line:
47,XX,+mar[11]/
46,XX[34]
inv dup(14)(q11.1) see 14-O-q11.1/1-31 n.a. 12L0086  
  EKF-
#14-q11.1/
5-i
in cell line:
47,XY,+mar[48]
inv dup(14)(q11.1) see 14-O-q11.1/1-11 n.a. 12L0134  
  EKF-
#14-q11.1/
6-i
in cell line:
47,XX,+mar mat[48]
inv dup(14)(q11.1) see
14-O-q11.1/1-30
n.a. 12L0222  
  EKF-
#15-N/
1-i
47,XX,+mar[4]/
46,XX[46]
inv dup(15)(qterq24.1:
:q24.1
qter)
see 15-N-qt23/1-2 n.a. 05P0753  
  EKF-
#15-q10/
1-i
in cell line:
47,XY,+mar[90]/
46,XY[10]
inv dup(15)(q10) see 15-O-q10/1-7 n.a. 12L0090  
  EKF-
#15-q11/
1-m
in cell line: 47,XX,+mar[58]/
46,XX[42]
min(15)(:p11q11:) see 15-O-q11/4-2 n.a. 12L0087  
  EKF-
#15-q11/
1-i
in cell line:
47,XY,+mar[9]/
46,XY[91]
inv dup(15)(q11) see 15-O-q11/1-1 n.a. 12L0105  
  EKF-
#15-q11.1/
1-r
in cell line: 47,XX,+mar[26]/
46,XX[74]
r(15)(::p11.1q11.1::) see 15-W-q11.1/1-1 n.a. 12L0094  
  EKF-
#15-q11.1/
1-m
in cell line: 47,XX,+mar[0]/
46,XX[50]
min(15)(:p11.1q11.1:) see 15-U-24 n.a. 12L0123  
  EKF-
#15-q11.1/
1-i
in cell line: 47,XX,+mar[19]/
46,XX[81]
inv dup(15)(q11.1) see 15-O-q11.1/1-22 n.a. 07PO019  
  EKF-
#15-q11.1/
2-i

in cell line: 47,XX,+mar[28]/
46,XX[72]

inv dup(15)(q11.1) see 15-O-q11.1/1-10 n.a. 12L0091  
  EKF-
#15-q11.1/
3-i
in cell line: 47,XX,+mar[99]/
46,XX[1]
inv dup(15)(q11.1) see 15-O-q11.1/1-21 n.a. 12L0112  
  EKF-
#15-q11.1/
4-i
in cell line:
47,XY,+mar[51]
inv dup(15)(q11.1) see
15-O-q11.1/1-62
n.a. 12L0183  
  EKF-
#15-q11.1/
5-i
in cell line:
47,XY,+mar[41]/
46,XY[6]
inv dup(15)(q11.1) see 15-O-q11.1/1-49 n.a. 12L0169  
  EKF-
#15-q11.1/
6-i
in cell line:
47,XX,+mar mat[7]/
46,XX[46]
inv dup(15)(q11.1) mother of
15-O-
q11.1/1-11
n.a. 12L0148  
  EKF-
#15-q11.1/
7-i
in cell line:
47,XY,+mar[28]/
46,XY[21]
inv dup(15)(q11.1) see 15-W-q11.1/3-2
n.a. 12L0133  
  EKF-
#15-q11.1/
8-i
in cell line:
47,XX,+mar[48]/
46,XX[0]
also in son and daughter cell lines 100% sSMC
inv dup(15)(q11.1) see
15-O-q11.1/1-16
mother of two normal children with same sSMC
EKF-#15-q11.1/8-i-son
EKF-
#15-q11.1/
8-i-daugther

12L0212
12L0213
12L0214

 
  EKF-
#15-q11.1/
9-i
in cell line:
47,XX,+mar[50/
46,XX[0]
inv dup(15)(q11.1) see
15-O-q11.1/1-77
n.a.

12L0142

 
  EKF-
#15-q11.1/
10-i
in cell line:
47,XX,+mar[50]
inv dup(15)(q1?1.1) see
15-O-q11.1/1-80
n.a.

12L0143

 
  EKF-
#15-q11.1/
11-i
in cell line:
47,XY,+mar[57]/
46,XY[1]
inv dup(15)(q11.1) see
15-O-q11.1/1-85
n.a.

12L0221

 
  EKF-
#15-q11.1/
12-i
in cell line:
47,XX,+mar[46]
inv dup(15)(q11.1) see
15-O-q11.1/1-81
n.a.

12L0305

 
  EKF-
#15-q11.1-
q13/
1-i
47,XX,+mar[25%]/
46,XX[75%]
der(15)(:q14q13:
:q14
p11.1:
:p11.1
q14:
:q13
q14:)
FISH-data: UBE3A at 23.2MB on sSMC
see
15-W-q14/4-1
EKF-#15-
q11.1-
q13/1-i-
mother;
EKF-#15-
q11.1-
q13/1-i-
father

2009B052
2009B050
2009B051

 
  EKF-
#15-q11.2/
1-i
in cell line:
47,XY,+mar[15]/
46,XY[85]
inv dup(15)(q11.2) see 15-O-q11.2/1-6 n.a. 2008B026  
  EKF-
#15-q11.2/
2-i
in cell line: 47,XY,+mar[97]/
46,XY[3]
inv dup(15)(q11.2)
FISH-data:  RP11-307C10 at 20.6MB on sSMC; RP11-131I21 at 22.73Mb not on sSMC
see 15-O-q11.2/1-13 n.a. 12L0101  
  EKF-
#15-q11.2
~12/
1-i
in cell line:
47,XX,+mar[96]/
46,XX[4]
inv dup(15)(q11.2~q12) see
15-O-q11.2~12/1-2
n.a. 06P0226  
  EKF-
#15-q12/
1-i
in cell line:
47,XY,+mar[50]
inv dup(15)(q12)
FISH-data:  RP11-171C8 at 23.0MB on sSMC
see 15-W-q12/1-1 n.a. 12L0141  
  EKF-
#15-q12~13/
1-i
in cell line:
47,XY,+mar[49]/
46,XX[1]
inv dup(15)(q12~13) see
15-CWw-148
n.a. 12L0258  
  EKF-
#15-q13/
1-i
in cell line:
47,XX,+mar[19]/
46,XX[32]
inv dup(15)(q13)
FISH-d
ata: SNRPN at 22.8MB on sSMC
see
15-W-q13/1-11
n.a. 12L0265  
  EKF-
#15-q13.1/
1-r
in cell line:
47,XX,+mar[30]/
46,XX[19]
r(15)
(::p11.2
q13.1::)
FISH-d
ata: SNRPN at 22.8MB on sSMC
see
15-O-q13.1/1-1
n.a. 12L0269  
  EKF-
#15-q14/
1-i
in cell line:
47,XX,+mar[49]/
46,XX[1]
inv dup(15)(q14) see 15-Caw-55 n.a. 12L0131  
  EKF-
#15-q14
q13.2q13.3/
1-i
in cell line:
48,XY,+marx2[50]
der(15)(pterq13.1~13.2: :q13.3q14::q14q13.3: :q13.1~13.2pter) see 15-W-q13.3+ q13.2+q14/1-1 EKF-#15-q14
q13.2q13.3/
1-i-mother;
EKF-#15-q14
q13.2q13.3/
1-i-father
11L369
11L370
11L371
 
  EKF-
#16-p11.2/
1-r
47,XY,+mar[5]/ 46,XY[27%] r(16)(::p11.2q12.1::)
aCGH: 9,875,000-35,005,000 MB
see 16-W-p11.2/3-3 EKF-#16-p11.2/
1-r-mother
EKF-#16-p11.2/
1-r-father
12L0138
13L0248 13L0247
 
  EKF-
#16-p11.1/
1-m
in cell line:
47,XY,+mar[8]/
46,XY[92]
min(16)(:p11.1q12.1:) see 16-O-p11.1/4-2 n.a. 06PO100 2005B290  
  EKF-
#17-p11.1/
1-i
47,XY,+mar[100%] dic(17)(:p11.1q11.1:
:q11.1
q11.2:)

see
17-U-4

n.a. 12L0186  
  EKF-
#18-pter/
1-i
in cell line: 47,XX,+mar[99]/
46,XX[1]
i(18p)
pter-0.36MB of q-arm
see 18-Wi-139 n.a. 12L0053  
  EKF-
#18-p11.21/
1-m
47,XY,+mar[21]/
46,XY[2]
FISH: min(18)(:p11.21q11.1:)
array + FISH:
min(18)(:p11.22
p11.21:)
FISH-data: RP11-151D11(13.08MB) on sSMC
array: 13.99MB - centromere
see 18-O-p11.21/1-2 n.a. 05P0294  
  EKF-
#18-p11.21/
2-m
47,XX,+mar[26]/
46,XX[14]
FISH: min(18)(:p11.21q11.1:)
breakpoint 
in 18p between  clone RP11-794M8 (13.03MB) and RP11-411B10 (13.99MB)
 see 18-O-p11.21/1-3 n.a. 12L0132   
  EKF-
#18compl#8/
1-m
in cell line:
47,XY,+mar[100]
der(18)t(8;18)(p23.2~23.1;q11.1) see 18-U10 n.a. 06P0222  
  EKF-
#18-q11.1/
1-i
47,XY,+mar[100%] i(18)(p10) see 18-Wi-143 EKF-#18-
q11.1/1-i-mMother; EKF-#18-
q11.1/1-i-
father
2007B279
2007B277
2007B278
 
  EKF-
#19-p13.1/
1-m
in cell line:
47,XY,+mar[9]/
46,XY[47]
min(19)(:p13.11~13.12q12:) see 19-W-p13.1/3-1  n.a. 12L0085  
  EKF-
#19-p13.11/
1-m
in cell line:
47,XX,+mar[0]/
46,XX[31]
min(19)(:p13.11q12:) 
FISH-data:
26.7-at least to 33.3MB
see 19-U-7 n.a. 05P0067  
  EKF-
#19-p13.11/
2-m
in cell line:
47,XX,+mar[21]/
46,XX[34]
min(19)(:p13.11q11~12:) 
FISH-data: RP11-22G10 (22.98MB) on sSM
C
see 19-O-p13.11/1-1 n.a. 12L0140  
  EKF-
#19-p13.11/
2-r
in cell line:
47,XX,+mar[0]/
46,XX[50]
min(19)(:p13.11q11:)[3]/
r(19)(::p13.11
q11::)[9]/
r(19)(::p13.11
q11:
:p13.11
q11::)[2]
FISH-data: RP11-22G10 (22.98MB) on sSM
C
aCGH: 17.50-33.59
see 19-O-p13.11/3-1 n.a. 2008B073  
  EKF-
#19-p12/
1-m
in cell line:
47,XY,+mar[11]/
46,XY[50]
min(19)(:p12q12:)
size in p 2.59MB (= position 25.91 MB) , in q 2.3 MB (= position 32.4MB)
see 19-W-p12/2-1 EKF-#19-
p12/1-m-
father
12L0089
13L0134
 
  EKF-
#19-p12/
2-m
in cell line:
47,XY,+mar[4]/
46,XY[48]
min(19)(:p12q13.11~13.12:)
size in p: RP11-22G10 in subcenM present on sSMC (22.98 MB - no signal in p on array)
, in q according to array: sSMC goes to 36.3 MB
see 19-W-p12/5-1 n.a. 12L0127  
  EKF-
#19-p12/
3-m
in cell line:
47,XY,+mar[9]/
46,XY[51]
min(19)(:p12q13.1?1:) see 19-W-p12/5-2 n.a. 12L0253  
  EKF-
#19-p11.1/
1-m
in cell line:
47,XX,+mar[0]/
46,XX[50]
min(19)(:p11.1q13.1:)
FISH-d
ata: RP11-14D17 (36.90MB) on sSMC
see 19-O-p11/1-1 n.a. 05P0277  
  EKF-
#20-p11.22
~11.21/1-m
47,XX,+mar[7]/
46,XX[4]
min(20)(:p11.22~11.21
q11.21~11.22:)
see 20-W-p11.22/1-2 n.a. 12L0164  
  EKF-
#20-p11.1/
1-m/r
47,XX,+mar[20] 47,XX,+min(20)(:p11.1q11.22:)[18]/47,XX,+min(20)(:q11.22p11.1::p11.1q11.22:)[7]/
47,XX,+r(20)(::p11.1
q11.22::p11.1q11.22::)[3]/46,XX[2]
see
20-W-p11.1/1-1
n.a. 12L0257  
  EKF-
#21-q21.1/
1-i
in cell line: 47,XY,+mar[149]/
46,XY[1]
inv dup(21)(q11.2)
FISH-d
ata: RP11-89H21 (14.85MB) on sSMC
see 21-O-q11.2/2-1 n.a. 12L0092  
  EKF-
#21-q11.2~
21.1/
1-m
in cell line:
47,XY,+mar[0]/
46,XY[92]
min(21)(pterq11.2~21.1:) see
21- W-q11.2~
21.1/ 1-2
EKF-#21-
q11.2~21.1/1-m-mother;
EKF-#21-
q11.2~21.1/1-m-father

06P0503 06P0503-A
07P0285
07P0284

 
  EKF-
#22-q11.1/
1-m
in cell line:
47,XX,+mar[8]/
46,XX[44]
min(22)(:p11.1q11:)
maternal UPD 22
see
22-O-q11/2-1
EKF-#22-q11.1/
1-m-mother;
EKF-#22-q11.1/
1-m-father
12L0093
13L0215
13L0214
 
  EKF-
#22-q11.1/
1-i
in cell line:
47,XX,+mar[44 or 9]/
46,XX[4 or 21]
inv dup(22)(q11.1) see 22-O-q11.1/1-11 n.a. 2007B188
07PO490
 
  EKF-
#22-q11.1/
2-i
in cell line:
47,XY,+mar pat[40]/
46,XY[11]
inv dup(22)(q11.1) see 22-O-q11.1/1-14 n.a. 2008B140  
  EKF-
#22-q11.1/
3-i
in cell line:
47,XY,+mar[46]/
46,XY[4]
inv dup(22)(q11.1) see 22-O-q11.1/1-13 n.a. 2008B136  
  EKF-
#22-q11.1/
4-i
in cell line:
47,XX,+mar[51]
inv dup(22)(q11.1) see 22-O-q11.1/1-21 n.a. 2008B246  
  EKF-
#22-q11.1/
6-i
in cell line:
47,XX,+mar mat[50]

in cell line of mother:
47,XX,+mar[50]
inv dup(22)(q11.1) see 22-O-q11.1/1-22 EKF-#22-q11.1/
6-i-mother;

12L0104
12L0103

 
  EKF-
#22-q11.1/
7-i
47,XY,+mar[100%] inv dup(22)(q11.1) see 22-O-q11.1/1-38 n.a. 11L351  
  EKF-
#22-q11.1/
8-i
in cell line:
47,XY,+mar mat[50]

in cell line of mother:
47,XX,+mar[47]/
46,XX[2]
inv dup(22)(q11.1) see 22-O-q11.1/1-23 EKF-#22-q11.1/
8-i-mother;

12L0108
12L0109

 
  EKF-
#22-q11.1/
9-i
in cell line:
47,XY,+mar mat[25]/
46,XY[24]

in cell line of mother:
47,XX,+mar[43]/
46,XX[7]
inv dup(22)(q11.1) see 22-O-q11.1/1-33 EKF-#22-q11.1/
9-i-mother;

12L0115
12L0116

 
  EKF-
#22-q11.1/
10-i
in cell line: 47,XX,+mar[100%] inv dup(22)(q11.1) see 22-W-q11.1/1-5 n.a. 12L0118  
  EKF-
#22-q11.1/
11-i
in cell line: 47,XX,+mar[53] inv dup(22)(q11.1) see 22-O-q11.1/1-31 n.a. 12L0121  
  EKF-
#22-q11.21/
1-i
in cell line: 47,XX,+mar[48]/
46,XX[2]
inv dup(22)(q11.21) see
22-Wces-5-93
n.a. 05PO209  
  EKF-
#22-q11.21/
2-i
in cell line:
47,XY,+mar[26]/
46,XY[28]
inv dup(22)(q11.21) see 22-O-q11.21/2-1 n.a. 12L0088  
  EKF-
#22-q12.1/
1-m
in cell line:
47,XY,+mar[41]/
46,XY[9]
min(22)(pterq12.1:)
FISH-data:
pter to 24.6MB
see 22-W-q12.1/1-1 n.a. 06P0775  
  EKF-
#22compl#11/
1-m
in cell line: 47,XX,+mar[97]/
46,XX[3]
der(22)t(11;22)
(q23;q11.2)
see
22-Wder-143
EKF-#22compl#11
/1-m-mother;
EKF-#22compl#11/1-m-father;
12L0098 12L0099 12L0100  
  EKF-
X-p11.3/
1-m/r
45,X[93]/
46,X,+mar[7]
r(X)(::p11.3q21.1::)[2]/
min(X)(:p11.3
q21.1:)[3]/
min(X)(:p11.21
q11.2:)[2]
minX-p11.3/3-1 n.a. 12L0139  
  EKF-
Y-p11.2/
1-m
45,X[3]/46,X,mar[4]/
46,Xr(Y(::q12→q11.1:
:p11.2→p11.3::),[2]/
47,X,r(Y)(::q12→q11.1:
:p11.2→p11.3::)
,+mar(Y)[2]
r(Y) = min(Y)(:p11.2q11.1:) see
m-minY-p11.2/1-1
n.a. 12L0264  
  EKF-
Y-q11.22/
1-i
in cell line:
45,X[19]/
46,X,der(Y)[45]
inv dup(Y)(q11.22) see
m-iY-q11.22/1-3
n.a. 12L0110  
  EKF-
Y-q11.2/
1-r
46,XY/
46,X,der(Y)
i(Y)(q11.2)/
der(Y)(pter
q11.2::p11.31p11.31:) or  r(Y)(::p11.32q11.2::p11.31p11.31::)
see
m-rY-p11.32/5-1
n.a. 13L0223  
  EKF-
mult#4-#18/
1-i/m
48,XX,+mar1,+mar2[101]/
47,XX,+mar1[38]/
47,XX,+mar2[29]/
46,XX[5]
min(4)(:p12q12:); r(18)(::p11.21q11.2:
:p11.21
q11.2::)[2]/
inv dup(18)(:p11.1
q11.1:
:q11.1
p11.1:)[4]/
min(18)(:p11.21
q11.1:
:q11.1
p11.1:)[4]
chr 4: 48.34-59.71
chr. 18: 13.17-18.73
see
mult 2-18
n.a. 05P0163  
  EKF-
mult#5-#6/
1-m/r
49,XX,+3mar[1]/
48,XX,+2mar[10]/
47,XX,+mar[9]/
46,XX[3]
r(5)(::p11q11.1:
:q12
13.1~3::)
40.66MB to 47.10MB 
min(6)(:p11.1
q11.2:);
57.10MB to 64.87MB
see
mult 2-19
n.a. 2010B194  
  EKF-
mult#8-#21/
1-m/r
49,XY,mar2x2[7]/
48,XY,mar1,mar2[52]/
47,XY,mar1[37]/
46,XY[4]
r(8)(:p12q11.1:
:
q11.1p21.1:),
min(8)(:p11.22
q11.21:
:q11.21
p21.1::p21.1
p11.22:) [70%],
min(21)(:p11.1
q21.3:) [30%]
chr 8: 28.63-48.74 MB
chr 21: 13.30-28.90 MB
see
mult 2-21
n.a. 05P0208  
  EKF-mult
#1-#3-#11-
#14-#20-#21-X/
1-m/r
49-53,XY,+mar1-7[100%] r(11) in ~84%
?r(1) in ~90%
?r(3) in ~80%
min(X) in ~88%
min(20) in ~74%
min(14) in ~94%
min(21) in ~83%
see
mult 7-1
n.a. 165014
(
provided by Drs. Fryns and Vermeesch. Leuven Belgium)
 
  EKF-
mult#4-#8-#11/
1-r
49,XY,+3mar[13]/
48,XY,+2mar[22]/
47,XY,+mar[23]/
46,XY[2]
r(4)(::p12q12::)
r(8)(::p11.21
q11.21::)
r(11)(::p11.12
q11.1::)
see
mult 3-5
EKF-mult#4-
#8-#11/1-r-
mMother; EKF-mult#4-
#8-#11/1-r-father
2010B110
1010B108
2010B109
 
  EKF-
N/
1-i
47,XY,+mar[100%] mar stains only with a reverse painting probe of itself see
u-W-1
n.a. (provided by Dr. Caroline Mackie Ogilvie, UK)  
               

 

 

 


Nomenclature of the cell lines in the Else Kröner-Fresenius cellbank

 

Explanation using following example: EKF-#1-p11.1/1-r

EKF Else Kröner-Fresenius-foundation
 #1 to #22, X, Y chromosome sSMC is derived from
p11.1 distal chromosomal breakpoint
 /1- number of case(es) with identical breakpoints
 i/m/r  shape of sSMC as inverted duplicated, centric minute or ring

 

other abbreviations used:

compl                 
complex (rearranged) sSMC                                                   
mult multiple sSMC
N neocentric